13
Nov
2013
Irritable bowel syndrome (IBS) is characterized by chronic visceral pain. In IBS patients, the visceral hypersensitivity (VH) involves peripheral and central influences. In animals, VH can be induced by TNBS intracolonic injection or partial restraint stress (PRS). In humans, a recent pilot study has shown the efficacy of these probiotics (Lcr Restituo® and Lcr Lenio®). The aim of this study is to investigate the effects of these probiotic strains in TNBS- and stress-induced VH.